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Alkyllithium Compounds Bearing Electrophilic Functional Groups: A Flash Chemistry Approach
Aiichiro Nagaki1, Hiroki Yamashita1, Katsuyuki Hirose1
1Department of Synthetic and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto, 615-8510, Japan.
Abstract:
Flash chemistry based on flow microreactor systems allowed alkyllithiums bearing electrophilic functional groups to be successfully generated and used for subsequent reactions. The series of reactions with high reactivity was achieved by extremely accurate control over residence time in a controlled and selective manner.
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