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Pancreatic Choristoma in a Canine Gallbladder
Y Abou Monsef1, S Atalay Vural1, O Kutsal1
1Department of Pathology, Faculty of Veterinary Medicine, Ankara University, Ankara, Turkey.
Journal of Comparative Pathology
|January 30, 2019
Summary
A Siberian Husky with neurological issues was found to have pancreatic choristoma, a rare gallbladder tumor, during necropsy. This marks the first documented case of this condition in a canine gallbladder.
Area of Science:
- Veterinary Pathology
- Canine Medicine
- Surgical Pathology
Background:
- Canine distemper virus (CDV) infection can cause severe neurological disease in dogs.
- Pancreatic choristomas are rare congenital anomalies consisting of ectopic pancreatic tissue.
- Gallbladder lesions are uncommon in canine pathology reports.
Observation:
- A 1.5-year-old male Siberian Husky presented with progressive twitching and tetraplegia, ultimately requiring euthanasia.
- Necropsy revealed an incidental intramural white lesion in the gallbladder, measuring 10 × 15 × 5 mm.
- Histological examination identified the gallbladder lesion as pancreatic tissue within the tunica adventitia.
Findings:
- Immunohistochemistry confirmed the presence of pancreatic islets positive for insulin but negative for glucagon.
- The gallbladder lesion was diagnosed as pancreatic choristoma.
- The dog also exhibited non-suppurative meningoencephalitis secondary to canine distemper virus infection.
Implications:
- This case represents the first description of pancreatic choristoma in a canine gallbladder.
- The incidental finding highlights the importance of thorough necropsy examination, even in cases with concurrent severe disease.
- Understanding ectopic tissue presentation is crucial for veterinary diagnostics and research.
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