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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Asthma-III: Symptoms and Complications01:24

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Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
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Asthma-IV: Diagnostic and Management01:30

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The diagnosis and management of asthma are comprehensive, encompassing clinical assessments, lung function tests, and pharmacological interventions. Here's an overview:
Clinical Assessment for Asthma:
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma-IV: Nursing Management01:30

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The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
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The Exposome and Asthma.

Ahila Subramanian1, Sumita B Khatri2

  • 1Department of Allergy and Clinical Immunology, Respiratory Institute, Cleveland Clinic, Cleveland Clinic Lerner College of Medicine, CWRU School of Medicine, 9500 Euclid Avenue/A90, Cleveland, OH 4419, USA.

Clinics in Chest Medicine
|January 30, 2019
PubMed
Summary

The exposome, encompassing environmental exposures throughout life, interacts with genetic susceptibility to influence asthma development. Understanding these environmental factors is crucial for effective asthma management and advocacy.

Keywords:
Air pollutionAllergenAsthmaClimate changeExposome

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Area of Science:

  • Environmental Health
  • Epidemiology
  • Genetics

Background:

  • Asthma pathogenesis is influenced by complex interactions between individuals and their environments.
  • Both indoor and outdoor environmental exposures contribute to disease development.
  • Genetic susceptibility plays a key role in asthma initiation and progression.

Purpose of the Study:

  • To highlight the significance of the exposome in asthma.
  • To emphasize the interplay between environmental factors and host genetics in asthma.
  • To underscore the need for awareness of global environmental changes for health professionals.

Main Methods:

  • Literature review on exposome and asthma.
  • Analysis of environmental exposure data.
  • Consideration of genetic predisposition in asthma.

Main Results:

  • Environmental exposures, varying in level and duration, are implicated in asthma.
  • The exposome significantly modifies the impact of genetic susceptibility on asthma.
  • Global environmental changes present challenges for asthma management.

Conclusions:

  • A comprehensive understanding of the exposome is vital for addressing asthma.
  • Integrating environmental and genetic information is key to personalized asthma care.
  • Health professionals must be informed about environmental exposures to advocate effectively.