Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Right ventricular function in cor pulmonale.

W MacNee1

  • 1Department of Respiratory Medicine, Rayne Laboratory, City Hospital, Edinburgh, UK.

Cardiology
|January 1, 1988
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Erratum to: Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

Clinical and translational allergy·2017
Same author

ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle.

Clinical and translational allergy·2017
Same author

Building Bridges for Innovation in Ageing: Synergies between Action Groups of the EIP on AHA.

The journal of nutrition, health & aging·2016
Same author

Scaling up strategies of the chronic respiratory disease programme of the European Innovation Partnership on Active and Healthy Ageing (Action Plan B3: Area 5).

Clinical and translational allergy·2016
Same author

A genome-wide analysis of the response to inhaled β2-agonists in chronic obstructive pulmonary disease.

The pharmacogenomics journal·2015
Same author

Systemic Effect of Particulate Air Pollution.

Inhalation toxicology·2015
Same journal

Aortic Valve Sclerosis: More Than an Incidental Echocardiographic Finding.

Cardiology·2026
Same journal

Can resting segmental strain identify obstructive coronary artery disease in chronic coronary syndrome patients referred to CABG?

Cardiology·2026
Same journal

Mortality Impact of Stroke and Major Bleeding Across the Ejection Fraction Spectrum in Patients Hospitalized for Acute Heart Failure With Prevalent Atrial Fibrillation.

Cardiology·2026
Same journal

Impact of Inflammatory Disorders on Outcomes in Acute Heart Failure: A Nationwide Analysis.

Cardiology·2026
Same journal

Predictors and Clinical Impact of Tricuspid Regurgitation After Pericardiectomy for Constrictive Pericarditis.

Cardiology·2026
Same journal

Utilization of Guideline-Directed Medical Therapies and Transcatheter-Edge-to-Edge Repair in Patients with Significant Secondary Mitral Regurgitation.

Cardiology·2026
See all related articles

Right ventricular function in chronic obstructive pulmonary disease (COPD) with pulmonary hypertension is surprisingly normal when stable. However, oxygen therapy improves survival, though not necessarily via direct cardiac effects.

Area of Science:

  • Cardiology
  • Pulmonology
  • Respiratory Medicine

Background:

  • Pulmonary arterial hypertension (PAH) and cor pulmonale are linked to poor prognosis in hypoxic chronic obstructive pulmonary disease (COPD).
  • Traditionally, the right ventricle (RV) is considered to function poorly under increased afterload.

Purpose of the Study:

  • To investigate RV contractility in clinically stable COPD patients with PAH.
  • To evaluate the impact of clinical stability and edema on RV function in COPD patients with PAH.

Main Methods:

  • Assessment of RV contractility using the right ventricular end-systolic pressure/volume relationship.
  • Comparison of RV function in stable COPD patients versus those presenting with edema.

Main Results:

Related Experiment Videos

  • RV contractility was found to be relatively normal in stable COPD patients with PAH.
  • RV function was reduced in COPD patients with PAH who presented with edema.
  • Continuous oxygen therapy is the only proven survival-improving treatment for COPD and cor pulmonale, but its cardiac effects are unclear.

Conclusions:

  • RV function in COPD with PAH may be preserved when clinically stable.
  • Edema indicates a decline in RV function in this patient population.
  • The survival benefit of oxygen therapy in COPD and cor pulmonale may not be directly mediated by improved cardiac function.