[Postprandial Abdominal Fullness after Pylorus-Preserving Gastrectomy for Early Gastric Cancer]

To clarify the basis for postprandial abdominal fullness(PAF)in patients after pylorus-preserving gastrectomy(PPG), the authors investigated the relationship of PAF with postgastrectomy disorder(PGD)and gastric emptying function(GEF)in PPG patients. A total of 22 patients(14 men and 8 women, average age 64.8 years)were divided into 2 groups[Group A, PAF-positive(n=12); Group B, PAF-negative(n=10)]at 1 year after PPG for early gastric cancer. The relationships of PAF with PGD and GEF were examined. Length of the antral cuff(LAC)was significantly shorter in group A than in group B(p< 0.05). Appetite and food consumption per meal were significantly greater in group B than in group A(p<0.05 and p<0.01, respectively). Symptomatic reflux esophagitis(RE), early dumping syndrome, decreased percent body weight before illness, endoscopic RE, and endoscopic gastritis in the remnant stomach were more common in group A than in group B. Gastric stasis in the remnant stomach was significantly more common in group A than in group B(p=0.0071). GEF for solid food [time to 50%residual rate in the remnant stomach(minutes)and residual rate at 120 minutes in the remnant stomach(%)] in group A was significantly delayed compared with that in group B(p<0.001). Patients with PAF showed shorter LAC, delayed GEF for solid food, and worse postoperative quality of life(QOL), compared with those without PAF.