[Staging by TNM Classification of Two Cases of Advanced Appendiceal Carcinoma]

We report 2 cases of resected appendiceal carcinomas. Case 1: A 67-year-old woman. At surgery, multiple mucoid foci were observed in the peritoneal cavity. Laparoscopic right hemicolectomy(R2)was performed. The pathologic findings were a mixture of well-differentiated adenocarcinoma and well-differentiated mucinous carcinoma, grade 1, pStage ⅣA (pT2N0M1bG1). Six months after surgery, she is undergoing adjuvant chemotherapy at an outpatient clinic. Case 2: A 48- year-old woman. At surgery, invasion into the terminal ileum was observed. A laparoscopic right hemicolectomy resection (R0)was performed. The pathological diagnosis was Stage Ⅱ(pT4bN0M0). She has been followed-upat an outpatient clinic. Discussion: Case 1 had a relatively good prognosis if only well-differentiated mucinous carcinoma was seeded; however, because of the co-existence of well-differentiated adenocarcinoma, postoperative chemotherapy was performed. Case 2 was diagnosed with invasive mucinous carcinoma(grade 2), but because there was no dissemination or lymph node metastasis, follow-upfor Stage Ⅱ disease without adjuvant therapy was considered appropriate. Staging based on TNM classification appendiceal carcinoma cases is desirable for the prediction of prognosis and determination of the appropriate treatment strategy.