Correction to: NFATc2 is an intrinsic regulator of melanoma dedifferentiation

V Perotti1, P Baldassari1, A Molla1

  • 1Human Tumors Immunobiology Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Oncogene
|January 30, 2019
PubMed

Insights

This study corrects errors in blot images for MITF, MART-1, and β-actin in Fig. 6e. The scientific conclusions remain unaffected by these image presentation errors.

Area of Science:

  • Molecular Biology
  • Cell Biology
  • Cancer Research

Context:

  • The study involves the analysis of protein expression and modulation.
  • Specific proteins investigated include Microphthalmia-associated transcription factor (MITF), Melanoma Antigen Recognized by T-cells 1 (MART-1), and beta-actin (β-actin).
  • The research utilizes Western blot techniques to assess protein levels.

Purpose:

  • To correct erroneous Western blot images presented in a previous figure (Fig. 6e).
  • To ensure accurate representation of MITF, MART-1, and β-actin expression data.
  • To maintain the integrity and reproducibility of the research findings.

Summary:

  • Errors were identified in the Western blot images for MITF, MART-1, and β-actin in Fig. 6e.
  • These incorrect blots were due to similarity with images from a different figure (Fig. 5c).
  • Corrected blots have been provided in a revised figure within an associated Correction notice.

Impact:

  • The correction of these blots does not alter the interpretation of the results presented in Fig. 6e.
  • The overall conclusions of the research paper remain unchanged.
  • This ensures the scientific accuracy and reliability of the published findings despite the initial error.

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