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Intra- and inter-model reliability of Hemocue Hb 201+ and HemoCue Hb 301 devices
Ashish Jain1, Nilotpal Chowdhury2, Sanchit Jain3
1Department of Immunohematology and Blood Transfusion, Himalayan Institute of Medical Sciences, SRHU, Dehradun, Uttarakhand, India.
Aim:
The study intended to estimate the intra- and inter-model reliability and agreement between the HemoCue Models 201+ and 301 in a blood bank donor screening setting.
Materials And Methods:
Venous blood samples from 115 blood donors were analyzed by two Hemocue 201+ instruments and two HemoCue 301 instruments. The Lin's concordance correlation coefficient (CCC) as well as the Bland-Altman limits of agreement was measured.
Results:
The 95% lower confidence interval (CI) of all the CCCs had a value >0.90. The CCC between instruments belonging to the same model was compared to instruments belonging to different models. The mean of HemoCue 301 was higher than HemoCue 201+ by 3.04 g/L with the 95% CI of the differences (i.e., the limits of agreement) between the two models ranging from -3.35 to 9.44 g/L. The bias between two instruments was lesser, and the limits of agreement were even narrower between instruments belonging to the same model.
Conclusion:
The inter-instrument reliability and agreement are satisfactory in a blood bank setting.
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