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Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
Published on: June 28, 2021
Severe hypertriglyceridemia-induced pancreatitis successfully managed with therapeutic plasma exchange: Report from
Swati Pabbi Mehta1, Aseem Kumar Tiwari1, Rajesh Puri2
1Department of Transfusion Medicine, Medanta - The Medicity, Gurgaon, Haryana, India.
Abstract:
Hypertriglyceridemia (HTG) is the third most significant risk factor for acute pancreatitis after gallstones and alcohol. Therapeutic plasma exchange (TPE) has been considered a possible treatment for HTG-induced pancreatitis, especially in severe and refractory cases. Here, we report one such clinical experience with a patient of severe HTG-induced pancreatitis. He was treated with TPE along with intravenous insulin, statins, and fibrates. TPE resulted in immediate relief of symptoms as well as a marked improvement in laboratory values, with 74.5% reduction in triglycerides after a single session. TPE can be successfully utilized as an adjunct in HTG-induced pancreatitis.
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