Performance and Capacity Measurement of the Lower Extremities in Multiple Sclerosis -How to Approach?

Walking limitations play a key role in the development of disability in multiple sclerosis (MS) patients. Vast majority of patients, even in the very early stages of the disease, experience walking disturbances. Measuring capacity and performance in lower extremities enables us to 1) monitor disease pregression; 2) evaluate treatment responses; 3) determine the necessity of new treatment strategies on time. The purpose of this review is to highlight the importance of regular walking assessments in MS patients, give idea about which measurement tools to choose, and provide insight for future investigations in the light of new technological developments.