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Sinusitis and asthma: clinical and pathogenetic relationships.

G A Friday1, P Fireman

  • 1University of Pittsburgh School of Medicine, Pennsylvania.

Clinics in Chest Medicine
|December 1, 1988
PubMed
Summary

Sinusitis may be a cause of asthma, with a potential reflex linking the upper and lower airways. This review covers evidence for this link, plus sinusitis diagnosis and treatment.

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Area of Science:

  • Respiratory Medicine
  • Immunology

Background:

  • Sinusitis is increasingly recognized as a potential contributing factor to asthma development and exacerbation.
  • A proposed reflex pathway between the upper and lower airways suggests a mechanism linking sinusitis and asthma.

Purpose of the Study:

  • To review the evidence supporting and refuting the existence of an upper-airway-to-lower-airway reflex in the context of sinusitis and asthma.
  • To discuss current diagnostic approaches for sinusitis.
  • To outline contemporary management strategies for sinusitis.

Main Methods:

  • Literature review of studies investigating the relationship between sinusitis and asthma.
  • Analysis of evidence for and against the postulated reflex mechanism.
  • Summary of established diagnostic criteria and treatment guidelines for sinusitis.

Main Results:

  • Evidence suggests a complex interplay between sinusitis and asthma, with sinusitis potentially triggering or worsening asthma symptoms in susceptible individuals.
  • The existence and clinical significance of a direct reflex pathway remain under investigation, with some studies supporting and others challenging the concept.
  • Effective management of sinusitis may positively impact asthma control.

Conclusions:

  • Sinusitis is a relevant comorbidity in asthma management.
  • Further research is needed to elucidate the precise mechanisms, including reflex pathways, linking sinusitis and asthma.
  • Comprehensive diagnosis and treatment of sinusitis are crucial for optimizing patient outcomes in both conditions.

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