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Published on: November 14, 2020
Enhanced Recovery Protocol for Laparoscopic Sleeve Gastrectomy: Are Narcotics Necessary?
Richard S Hoehn1, Aaron P Seitz2, Kathleen E Singer2
1Department of Surgery, University of Cincinnati College of Medicine, 231 Albert Sabin Way, ML 0558, Cincinnati, OH, 45267, USA. Richard.Hoehn@uc.edu.
Enhanced recovery after surgery (ERAS) protocols significantly reduced narcotic use in laparoscopic sleeve gastrectomy patients. This approach shows promise for minimizing opioid reliance in bariatric surgery.
Area of Science:
- Bariatric Surgery
- Surgical Protocols
- Pain Management
Background:
- Enhanced Recovery After Surgery (ERAS) protocols improve patient outcomes.
- The opioid epidemic necessitates strategies to reduce narcotic use.
- Laparatic sleeve gastrectomy is a common bariatric procedure.
Purpose of the Study:
- To evaluate the impact of an ERAS protocol on postoperative narcotic usage.
- To assess changes in length of stay, complications, and readmissions.
- To determine the feasibility of reducing narcotic dependence after bariatric surgery.
Main Methods:
- Retrospective chart review of patients undergoing laparoscopic sleeve gastrectomy.
- Comparison of narcotic usage 6 months before and after ERAS protocol implementation.
- Analysis of intravenous and oral narcotic use, complications, and readmissions.
Main Results:
- ERAS implementation led to a significant reduction in intravenous (100% to 47%) and oral schedule 2 narcotic use (56% to 6%).
- Tramadol usage increased (0% to 36%) post-ERAS.
- 52% of patients were managed without schedule 2 narcotics, and 33% received no narcotics at all post-ERAS.
Conclusions:
- ERAS protocols dramatically reduce postoperative narcotic use in laparoscopic sleeve gastrectomy.
- This strategy offers a pathway to minimize opioid requirements in bariatric surgery.
- Potential for narcotic elimination in select patients and procedures.
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Enhanced Elimination of Poison
Antidotes serve a crucial role in counteracting the effects of poison by inhibiting enzymes responsible for producing harmful drug metabolites. In some cases, these toxic metabolites can be neutralized by endogenous cosubstrates, which are maintained at specific concentrations to prevent interaction with cellular macromolecules and subsequent cell death.
Renal excretion is the...

