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Updated: Jan 30, 2026

Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
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Published on: February 26, 2013

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Catheter Ablation of Long-standing Persistent Atrial Fibrillation: a Reckless Challenge or a Way to Real Cure?

Hui Nam Pak1

  • 1Division of Cardiology, Department of Internal Medicine, Yonsei University Health System, Seoul, Korea. hnpak@yuhs.ac.

Korean Circulation Journal
|January 30, 2019
PubMed

Insights

Treating long-standing persistent atrial fibrillation (L-PeAF) is challenging due to atrial remodeling. However, advancements in ablation strategies and patient selection are improving rhythm control outcomes for L-PeAF.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Long-standing persistent atrial fibrillation (L-PeAF) is defined as atrial fibrillation (AF) maintained for over one year, where rhythm control is attempted.
  • L-PeAF is characterized by significant electrical and structural atrial remodeling, making rhythm restoration difficult.

Purpose of the Study:

  • To review the evolution of rhythm control outcomes in L-PeAF.
  • To discuss future directions in managing L-PeAF.

Main Methods:

  • Review of current literature on L-PeAF management.
  • Analysis of advancements in mapping devices, ablation catheters, and patient selection criteria.

Main Results:

  • Rhythm control outcomes for L-PeAF are progressively improving.
  • Sophisticated mapping, efficient catheters, and evidence-based strategies enhance success rates.

Conclusions:

  • Despite challenges, L-PeAF management is advancing.
  • Optimized ablation strategies and patient selection are key to improving sinus rhythm maintenance.

Keywords:
Catheter ablationPersistent atrial fibrillationPulmonary veins

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