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Updated: Jan 30, 2026

Synthesis and Purification of Iodoaziridines Involving Quantitative Selection of the Optimal Stationary Phase for Chromatography
Published on: May 16, 2014
[Preparation and performance evaluation of a novel polar urea-propyl-C30 stationary phase]
Min Wei1, Xiaoqing Jin1, Yuexing Zhao1
1Academy of Chemistry and Life Sciences, Zhejiang Normal University, Jinhua 321004, China.
Abstract:
A novel polar urea-propyl-C30 (TPU-C30) reversed stationary phase was prepared by using 3-ureidopropyltrimethoxysilane as a coupling agent. The characteristics of TPU-C30 were analyzed by scanning electron microscopy, elemental analysis, infrared spectroscopy and thermal analysis. The results showed that the TPU-C30 stationary phase was successfully prepared. Furthermore, the relative deviations of the element contents of TPU-C30 were within 5% (n=3), which indicated that the proposed synthesis had good repeatability. The chromatographic performances in the stationary phase were evaluated by using different polar compounds, positional isomers and basic compounds as solute probes. Compared to the conventional C18 and C30 columns, the TPU-C30 stationary phase had different selectivity and better shape selection. The TPU-C30 stationary phase can be applied in various fields.
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