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Gastrointestinal mucormycosis in a child with acute lymphoblastic leukemia: An uncommon but ominous complication
Sidharth Totadri1, Shirley Sundersingh2, Ramya Natarajan2
1Department of Medical Oncology, Cancer Institute (WIA), Chennai, Tamil Nadu, India.
Abstract:
Invasive fungal infections constitute a major cause of morbidity and mortality in children undergoing therapy for hematological malignancies. We report a 1-year-old boy who was receiving chemotherapy for acute lymphoblastic leukemia. His clinical course was complicated by a clinical syndrome consistent with neutropenic enterocolitis to which he succumbed. Histopathology of the surgically resected bowel revealed evidence of mucormycosis. Gastrointestinal mucormycosis is an unusual presentation which requires high degree of clinical suspicion and aggressive management.
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