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Updated: Jan 30, 2026

Isolated Hepatic Perfusion as a Treatment for Liver Metastases of Uveal Melanoma
Published on: January 25, 2015
Patient preferences for treatment of metastatic melanoma
Carol Mansfield1, Briana Ndife2, Joyce Chen2
1RTI Health Solutions, Research Triangle Park, NC 27709, USA.
Aim:
To investigate patient preferences for clinical attributes of first-line metastatic melanoma treatments.
Materials & Methods:
A discrete-choice experiment and best-worst scaling exercise were used to assess relative preferences for treatment attributes.
Results:
The 200 survey respondents had distinct preferences. Avoiding a 30% risk of colitis or hormone gland problems and avoiding severe fever were more important to respondents than avoiding a 20% risk of extreme sun sensitivity (p < 0.05). Patients preferred taking pills to receiving intravenous infusions in a clinic. When attributes were combined, approximately 85% of respondents preferred a risk profile similar to targeted therapy over a profile similar to immunotherapy, holding efficacy constant.
Conclusion:
Taking patient preferences into account can help patients get the full benefit from metastatic melanoma therapies.
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