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Updated: Jan 30, 2026

In Vitro and In Vivo Delivery of Magnetic Nanoparticle Hyperthermia Using a Custom-Built Delivery System
Published on: July 2, 2020
Interaction energy and detachment of magnetic nanoparticles-algae
Yunfeng Xu1, Xin Wang1, Yu Fu2
1School of Environmental and Chemical Engineering, Shanghai University, Shanghai, People's Republic of China.
Abstract:
Magnetic separation, a promising bioseparation technology, is confronted with the challenges in recovery and recycle of magnetic matters during algae harvesting for biofuel extraction. The thermodynamic method was used to characterize the surface interactions between MNPs and algae cells. Three methods were adopted to detach magnetic nanoparticles-algae (Microcystis aeruginosa, Synechocystis sp., Nannochloropsis maritima and Stigeoclonium sp.) and recover magnetic nanoparticles (MNPs) in this study. The thermodynamic method indicated that the greatest adhesion strength was expected for Stigeoclonium sp. on MNPs. High detachment efficiency of MNP-algae was achieved by ultrasonic-extracting, which got above 90% after 5 recycles. Moreover, the harvesting efficiencies of these four algae cells could remain more than 90% after 5 recycles using a mixture of the regenerated and the raw MNPs.
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