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Updated: Jan 30, 2026

Teratoma Generation in the Testis Capsule
Published on: November 7, 2011
[Transformation of teratoma in rabdomiosarcoma]
Hernán J Cutuli1, Carolina Barciocco1, Érica Rojas Bilbao2
1Departamento de Oncología Clínica, Instituto de Oncología ángel H. Roffo, Universidad de Buenos Aires, Argentina.
Abstract:
Teratomas are malign germ cell tumors composed of two or more tissue layers. When there is specific organ differentiation they are called mature teratoma. They rarely grow aggressively. We report the case of a 29 year-old man with a diagnosis of gonadal germ cell tumor whose evolution was unfavorable owing to transformation into a different phenotype corresponding to a rhabdomyosarcoma. This phenomenon occurs through differential growth of a single histological component of the original tumor or transformation of a somatic lineage that becomes dominant. Transformed tumors such as the one herein described differ from most germ cell neoplasms regarding behavior, prognosis, and susceptibility to established treatments.
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