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Updated: Dec 31, 2025

Deep Proteome Profiling by Isobaric Labeling, Extensive Liquid Chromatography, Mass Spectrometry, and Software-assisted Quantification
Published on: November 15, 2017
[Upcoming Challenges of Next-Generation Clinical Laboratory Tests with Mass Spectrometric Technique -Chairman's
Abstract:
Many medical researchers and technologists have measured proteins, hormones, lipids, carbohydrates, and nucleotides in body fluids using conventional analytical techniques. After the 1990s, -omics devices includ- ing soft ionization mass spectrometry produced by Prof. John B Fenn and Dr. Koichi Tanaka en'abled us to more easily detect and identify new bioactive molecules in body fluids for the rapid and differential diagnosis of diseases. Especially, the MS techniques are leading to new breakthroughs in the fields of microorganism identification and pathological diagnosis. In this symposium, upcoming challenges of the modern MS techniques, such as electrospray ionization- and matrix-assisted laser desorption ionization-MS, in clinical tests for discovering biomarkers are being presented for the rapid diagnoses of infectious diseases and amyloidosis, and rapid detections of hormones and lipids in clinical samples by 4 speakers. [Review].
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