Related Experiment Video
Updated: Jan 30, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies
Published on: September 6, 2017
[FUNCTIONAL MORPHOLOGY OF BLOOD ERYTHROID CELLS IN NEOGOBIUS MELANOSTOMUS P. DURING CELL DIFFERENTIATION]
Abstract:
The morphometric characteristics of immature erythroid cells in circulating blood of the round goby (Neogobius melanostomus P) were studied: late basophilic normoblasts (BN), polychromatic normoblasts (PN), normocytes (mature erythrocytes). The linear sizes of the blood cells were assessed on photographs in the computer program ImageJ 1.44p. The sizes of the longitudinal and transverse axes of the cell and of its nucleus were determined. Using the appropriate algorithm, the following parameters were calculated: form index (MS), volume (Vc), area (Sc), thickness (h) and the specific surface area (SSc) of cells and nuc- lei as well as the nuclear-plasma ratio (NCR). The major changes occurred at the stage: PN - normocy- tes. They were aimed at improving the respiratory characteristics of cells. Besides accumulating hemoglobin in the cytoplasm and suppressing the functional activity of the nucleus, a significant increase in the diffusion surface of blood corpuscles was noted. As compared to BNs, S, and SS, of normocytes increased by 40 and 17 %, respectively, and the cells became ellipse-shaped. The processes underlying the formati- on of mature erythrocyte cytoskeleton are discussed.
More Related Videos
Related Concept Videos
iPS Cell Differentiation
B Cell Activation and Differentiation
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
Characteristics and Functions of Blood
The primary function of blood is to transport oxygen and carbon dioxide between tissues and the lungs. Oxygenated blood is bright red, while oxygen-depleted blood is darker. It also carries...
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Differentiation of Common Myeloid Progenitor Cells
Protein Buffers in Blood Plasma and Cells
Certain amino acids can exist in a zwitterion state at a...

