Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Nonlinear Pharmacokinetics: Causes of Nonlinearity

Nonlinear Pharmacokinetics: Causes of Nonlinearity

Nonlinearity in drug pharmacokinetics is caused by various factors influencing how a drug is absorbed, distributed, metabolized, and excreted. Understanding these nonlinear processes is crucial for predicting drug behavior in the body and optimizing drug dosing regimens.
Nonlinear drug absorption can occur when the process is rate-limited by solubility, carrier-mediated transport systems, or saturation of the presystemic gut wall or hepatic metabolism. For instance, high doses of riboflavin...

Limiting Reactant

Limiting Reactant

The relative amounts of reactants and products represented in a balanced chemical equation are often referred to as stoichiometric amounts. However, in reality, the reactants are not always present in the stoichiometric amounts indicated by the balanced equation.

Application of Nonlinear Inequalities

Application of Nonlinear Inequalities

A nonlinear inequality describes a comparison involving an expression that curves or behaves more complexly than a straight line. These inequalities often appear in forms that include squares, products, or variables in the denominator.To solve such an inequality, one starts by rewriting it so that zero appears on one side. For example, the inequality: can be factored as: This form makes it easier to identify the values that cause the expression to equal zero. In this case, the...

Introduction to Nonlinear Inequalities

Introduction to Nonlinear Inequalities

Linear and nonlinear inequalities are fundamental for analyzing variable relationships and identifying ranges satisfying specific conditions. A linear inequality involves variables raised only to the first power, resulting in a straight-line graph. This line partitions the coordinate plane into two distinct regions: one that satisfies the inequality and one that does not. Each region represents a set of solutions where the linear relationship holds true under the specified constraint.Nonlinear...

The Number e as a Limit

The Number e as a Limit

The number e is a fundamental constant in calculus, playing a central role in describing continuous change, particularly exponential growth. It is most naturally defined through its relationship with the natural logarithm, which is the inverse of the exponential function with base e. This relationship allows e to be characterized using basic principles of differentiation rather than as an arbitrary numerical constant.A key property of the natural logarithm function, ln x, is that its derivative...

Nonlinear Pharmacokinetics: Overview

Nonlinear Pharmacokinetics: Overview

Nonlinear or dose-dependent pharmacokinetics is a phenomenon that occurs when the pharmacokinetic parameters of certain drugs deviate from linear pharmacokinetics at higher doses. These drugs do not follow the expected first-order kinetics, where the rate of drug elimination is directly proportional to the drug concentration. Instead, they exhibit a nonlinear relationship, which can be attributed to several factors.
Nonlinearity can arise due to the saturation of plasma protein-binding or...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Synthesis and Stereochemical Revision of Violaceoid E, a Polyoxygenated Cyclohexanoid Natural Product Isolated from <i>Aspergillus violaceofuscus</i> Gasperini.

Journal of natural products·2026

Same author

Spatial photonic Ising machine: an emerging free-space optical computing architecture [Invited].

Applied optics·2026

Same author

Challenges and Countermeasures in Measuring Molecular Species of Characteristic Ingredients in Rice Bran Oil: Toward the Development of High-Quality Rice Bran Oil.

Journal of oleo science·2026

Same author

Roadmap on singular optics and its applications.

Applied physics. B, Lasers and optics·2026

Same author

Single-shot incoherent imaging with extended and engineered field of view using coded phase apertures.

Scientific reports·2026

Same author

Sub-diffraction ghost imaging with holographic pattern illumination.

Optics express·2025

Search research articles

Related Experiment Video

Updated: Jan 30, 2026

High-resolution Patterned Biofilm Deposition Using pDawn-Ag43

High-resolution Patterned Biofilm Deposition Using pDawn-Ag43

Published on: October 23, 2018

Resolution enhancement in nonlinear interferenceless COACH with point response of subdiffraction limit patterns.

Mani Ratnam Rai, A Vijayakumar, Yusuke Ogura

|January 31, 2019

Summary

Interferenceless coded aperture correlation holography (I-COACH) offers non-scanning 3D imaging. This technique achieves a 25% lateral resolution enhancement compared to direct imaging methods.

More Related Videos

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Published on: January 3, 2016

Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging

Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging

Published on: September 8, 2017

Related Experiment Videos

Last Updated: Jan 30, 2026

High-resolution Patterned Biofilm Deposition Using pDawn-Ag43

High-resolution Patterned Biofilm Deposition Using pDawn-Ag43

Published on: October 23, 2018

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Measurement of Scattering Nonlinearities from a Single Plasmonic Nanoparticle

Published on: January 3, 2016

Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging

Demonstration of a Hyperlens-integrated Microscope and Super-resolution Imaging

Published on: September 8, 2017

Area of Science:

Optics and Photonics
Digital Imaging
Holography

Background:

Conventional digital holography often requires scanning or complex setups.
Incoherent digital holography presents challenges in resolution and reconstruction.
Existing techniques may lack the resolution enhancement needed for detailed 3D imaging.

Purpose of the Study:

To introduce and validate Interfereless Coded Aperture Correlation Holography (I-COACH) for 3D imaging.
To demonstrate the resolution capabilities of I-COACH.
To engineer a novel coded phase mask (CPM) for enhanced holographic reconstruction.

Main Methods:

Developed a coded phase mask (CPM) using a modified Gerchberg-Saxton algorithm.
Generated a library of point object holograms for system calibration.
Employed non-linear cross-correlation for reconstructing 3D object planes.
Utilized a non-scanning, motionless, incoherent digital holography approach.

Main Results:

Achieved lateral and axial resolutions comparable to direct imaging with the same numerical aperture.
Demonstrated a lateral resolution enhancement of approximately 25% over direct imaging.
Successfully reconstructed various lateral sections of a 3D object.

Conclusions:

I-COACH is an effective technique for non-scanning, incoherent 3D digital holography.
The engineered CPM and cross-correlation method enable significant lateral resolution improvement.
I-COACH provides a promising alternative for high-resolution 3D imaging applications.