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Ptychographic X-ray computed tomography at a high-brilliance X-ray source
Optics Express
|January 31, 2019
Summary
Ptychographic X-ray computed tomography enables high-resolution 3D imaging. This study details a versatile method applicable to any brilliant X-ray source, expanding access to this advanced technique.
Area of Science:
- Physics
- Imaging Science
- Materials Science
Background:
- Ptychographic X-ray computed tomography (PXCT) offers nanometric resolution 3D imaging of refractive index.
- Current PXCT applications are limited to specialized synchrotron facilities.
Purpose of the Study:
- To present a universally applicable experimental procedure and data analysis pipeline for PXCT.
- To broaden the accessibility of PXCT beyond synchrotron sources.
Main Methods:
- Developed a detailed experimental protocol for PXCT.
- Created a comprehensive data analysis pipeline for PXCT data.
- Validated the procedure and pipeline at a high-brilliance X-ray source.
Main Results:
- Successfully applied PXCT to a biological sample.
- Demonstrated the efficacy of the developed procedure and pipeline.
- Achieved nanometric resolution imaging.
Conclusions:
- The presented PXCT method and pipeline are transferable to any high-brilliance X-ray source.
- This work significantly enhances the accessibility of advanced 3D imaging techniques.
- The successful application to biological samples opens new research avenues.
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