Incidence and prevalence of vitreomacular traction with and without macular hole in Germany

Jacob Menzler1, Aljoscha Steffen Neubauer1,2, Christos Haritoglou3

  • 1Institute for Health- and Pharmacoeconomics/Neubauer Consult, Munich, Germany, jacob.menzler@ifgph-muenchen.de.

Abstract

Insights

Symptomatic vitreomacular adhesion (sVMA) affects over 1.1 million people in Germany, with an annual incidence of 5,700 new cases. Many sVMA patients remain undiagnosed outside clinical settings.

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Public Health

Background:

  • Symptomatic vitreomacular adhesion (sVMA) includes vitreomacular traction (VMT) and macular holes (MHs).
  • Understanding the epidemiology of sVMA is crucial for healthcare planning.

Purpose of the Study:

  • To estimate the incidence and prevalence of sVMA in Germany.
  • To determine the number of vitrectomies performed for sVMA in Germany.

Main Methods:

  • Systematic literature review of international epidemiologic studies for sVMA incidence and prevalence.
  • Second systematic review to estimate the proportion of vitrectomies for sVMA in Germany.
  • Combined review data with national vitrectomy statistics for 2016.

Main Results:

  • Estimated sVMA prevalence: 1,365 per 100,000 population (1,119,300 cases in Germany).
  • Estimated sVMA incidence: 6.96 per 100,000 per year (5,700 new cases annually in Germany).
  • Approximately 2,300 vitrectomies performed annually for sVMA in Germany; ~1,700 for VMT.

Conclusions:

  • Population-based incidence is lower than expected from clinical data.
  • Suggests a significant number of sVMA patients are not currently within the healthcare system.
  • Highlights potential underdiagnosis and undertreatment of sVMA.

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