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Insights From Analysis of Human Antigen-Specific Memory B Cell Repertoires

Hemangi B Shah1, Kenneth Smith2, Jonathan D Wren2,3

  • 1Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States.

Frontiers in Immunology
|January 31, 2019
PubMed
Summary

Memory B cells provide immune memory but some pathogens impair their function. Analyzing these memory B cells and their antibody genes can improve future vaccine and antibody designs.

Keywords:
antibody repertoiresmemory B cellsmonoclonal antibodynext generation sequencingvaccination

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