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Updated: Jan 30, 2026

Contractility Measurements on Isolated Papillary Muscles for the Investigation of Cardiac Inotropy in Mice
Published on: September 17, 2015
Subdivision of the left ventricle by a discrete ridge and anomalous papillary muscle causing mid-ventricular
Ikuo Misumi1, Kota Motozato1, Hiroshige Yamabe1
1Department of Cardiology, Kumamoto Saisyunsou Hospital, Koshi City, Kumamoto, Japan.
Abstract:
A 16-year-old healthy boy visited our department because of a heart murmur. A 12-lead electrocardiogram showed left QRS axis deviation and repolarization abnormalities. Transthoracic echocardiography and a computed tomographic scan revealed a hypertrophied papillary muscle and a discrete ridge arising from the septal wall, causing mid-ventricular obstruction. Doppler echocardiography revealed that the pressure gradient at the obstruction was mild. The patient will be followed up annually, without medication or physical restriction.
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