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Effects of Peritoneal Dialysis on Clinical Factors and Functional Performance
Wenxiu Chang1, Ying Liu1, Ben-Chung Cheng2
1Department of Nephrology, Tianjin First Center Hospital, Tianjin, China.
Background:
We investigated the longitudinal trend of functional performance in peritoneal dialysis (PD) patients over 1 year after PD commencement and its related clinical parameters.
Methods:
One hundred and ninety-six PD patients were enrolled in this study. Karnofsky Performance Status Scale(KPSS) scores were used to assess functional performance. Patients were stratified into 3 groups according to the changes in KPSS from baseline to 1 year. A logistic regression analysis was performed to examine the associations of clinical parameters with KPSS changes.
Results:
Patients with KPSS declined showed older age and higher serum albumin concentration reduction within 1 year than those in KPSS improved and stable changes. Age was the significant risk factor for KPSS decline, while male and diabetes were significantly associated with non-declined KPSS by multivariable logistic regression analysis.
Conclusion:
The main determinants of KPSS trend were age, sex, and diabetes in new PD patients.
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