Related Experiment Video

Updated: Aug 16, 2026

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping
10:25

Brain Infarct Segmentation and Registration on MRI or CT for Lesion-symptom Mapping

Published on: September 25, 2019

[MRI in the diagnosis of lissencephaly. Apropos of a case]

C Bernard1, A Bajolle, P Droulle

  • 1Service de Radiologie, Hôpital d'Enfants, Vandoeuvre-les-Nancy.

Journal De Radiologie
|November 1, 1988
PubMed

Insights

This study highlights Magnetic Resonance Imaging (MRI) as the preferred method for diagnosing lissencephaly and other brain malformations, offering superior detail compared to CT scans.

Area of Science:

  • Neuroimaging
  • Developmental Neuroscience
  • Neuroradiology

Background:

  • Lissencephaly is a severe brain malformation characterized by a smooth brain surface due to defective neuronal migration.
  • Clinical presentation can vary, often including seizures and developmental delays.

Observation:

  • A patient presented with clinical signs of brain malformation.
  • Computed Tomography (CT) revealed lissencephaly with absent opercularization.
  • Electroencephalography (EEG) did not show typical hypsarrhythmia despite seizures.

Findings:

  • Magnetic Resonance Imaging (MRI) confirmed lissencephaly.
  • MRI identified associated anomalies: heterotopic grey matter and abnormal basal ganglia.
  • MRI demonstrated high grey-white matter contrast and multiplanar imaging capabilities.

Implications:

  • MRI is the imaging modality of choice for evaluating lissencephaly and other congenital brain malformations.
  • Detailed anatomical visualization aids in diagnosis and understanding the spectrum of malformations.
  • Advanced imaging techniques improve diagnostic accuracy in pediatric neurology.

More Related Videos

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy09:57

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy

Published on: September 20, 2024

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe06:04

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...