Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gene-Environment Interactions01:20

Gene-Environment Interactions

1.2K
Gene expression is a dynamic process that is significantly influenced by environmental factors. This interaction underlies the complex nature of biological development and the phenotypic differences observed among individuals, even among those with identical genetic makeups. Factors such as radiation, temperature, behavior, nutrition, and stress play pivotal roles in determining how genes are expressed. The concept of the reaction range is central to understanding this interaction. It posits...
1.2K
Adaptability of Cytoskeletal Filaments01:12

Adaptability of Cytoskeletal Filaments

6.0K
The cytoskeleton is a complex dynamic structure performing varied functions based on cellular requirements. The adaptability of the individual filaments in the cytoskeleton determines their ability to perform various functions within the cell. It can undergo rapid reorganization during processes like cell division or remain stable for several hours as in the interphase. The adaptability of these filaments depends on stringent regulatory mechanisms. The microfilament and microtubules of the...
6.0K
Natural Selection and Adaptation01:15

Natural Selection and Adaptation

1.4K
Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations,...
1.4K
Background and Environment Affect Phenotype02:27

Background and Environment Affect Phenotype

7.7K
Although the genetic makeup of an organism plays a major role in determining the phenotype, there are also several environmental factors, such as temperature, oxygen availability, presence of mutagens, that can alter an organism’s phenotype.
An example of how genetic background affects phenotype can be seen in horses. The Extension gene in horses is responsible for their coat color. A wild-type gene (EE) produces black pigment in the coat, while a mutant gene (ee) produces red pigment. A...
7.7K
Introduction to Innate and Adaptive Immunity01:21

Introduction to Innate and Adaptive Immunity

9.4K
The human immune system is a complex defense mechanism that protects the body from harmful pathogens and foreign substances. It comprises two crucial components: innate and adaptive immunity.
Innate immunity is the body's natural, nonspecific defense system that acts quickly to protect against pathogens. It incorporates physical barriers like skin and mucous membranes and cellular elements such as phagocytes and natural killer cells. This part of our immune system provides an immediate,...
9.4K
Adaptive Mechanisms in Cancer Cells02:53

Adaptive Mechanisms in Cancer Cells

7.1K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
7.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Insights into the mechanisms underlying cell wall-active agents and gentamicin bactericidal synergism against Enterococcus faecalis.

The Journal of antimicrobial chemotherapy·2026
Same author

Peptidoglycan recruitment by a penicillin binding protein.

Nature communications·2025
Same author

Developing a Learning Culture in Hospital Medicine.

Journal of Brown hospital medicine·2025
Same author

Evolutionary trajectories of β-lactam resistance in <i>Enterococcus faecalis</i> strains.

mBio·2024
Same author

Evolutionary trajectories of β-lactam resistance in <i>Enterococcus faecalis</i> strains.

bioRxiv : the preprint server for biology·2024
Same author

State-of-the-Art Review: Persistent Enterococcal Bacteremia.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America·2023

Related Experiment Video

Updated: Jan 30, 2026

A 1.5 Hour Procedure for Identification of Enterococcus Species Directly from Blood Cultures
05:02

A 1.5 Hour Procedure for Identification of Enterococcus Species Directly from Blood Cultures

Published on: February 10, 2011

24.3K

The Enterococcus: a Model of Adaptability to Its Environment.

Mónica García-Solache1, Louis B Rice2

  • 1Department of Medicine, Rhode Island Hospital, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA monica.garciasolache@cantab.net.

Clinical Microbiology Reviews
|February 1, 2019
PubMed
Summary

Enterococci are Gram-positive bacteria causing healthcare infections. Their resilience and adaptable genomes enable resistance to many antibiotics, complicating treatment.

Keywords:
Enterococcusantibiotic resistancehorizontal gene transfer

More Related Videos

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall
11:26

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall

Published on: July 31, 2015

13.0K
Visualizing Visual Adaptation
04:43

Visualizing Visual Adaptation

Published on: April 24, 2017

9.6K

Related Experiment Videos

Last Updated: Jan 30, 2026

A 1.5 Hour Procedure for Identification of Enterococcus Species Directly from Blood Cultures
05:02

A 1.5 Hour Procedure for Identification of Enterococcus Species Directly from Blood Cultures

Published on: February 10, 2011

24.3K
Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall
11:26

Adapting the Electrospinning Process to Provide Three Unique Environments for a Tri-layered In Vitro Model of the Airway Wall

Published on: July 31, 2015

13.0K
Visualizing Visual Adaptation
04:43

Visualizing Visual Adaptation

Published on: April 24, 2017

9.6K

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Antimicrobial Resistance

Background:

  • Enterococcus species are ubiquitous Gram-positive bacteria.
  • They are significant causes of healthcare-associated infections.
  • Enterococci are known for their resilience and adaptability to harsh environments.

Purpose of the Study:

  • To highlight the clinical significance of Enterococcus species.
  • To discuss the intrinsic and acquired antibiotic resistance mechanisms in Enterococcus.
  • To emphasize the challenges in treating Enterococcus infections.

Main Methods:

  • Literature review of Enterococcus epidemiology and resistance.
  • Analysis of intrinsic resistance profiles of Enterococcus species.
  • Examination of genetic mechanisms for acquired antibiotic resistance.

Main Results:

  • Enterococcus faecalis and Enterococcus faecium are the primary pathogens.
  • These bacteria exhibit intrinsic resistance to numerous antibiotics, including cephalosporins and aminoglycosides.
  • They readily acquire further resistance via mutation and horizontal gene transfer.

Conclusions:

  • Enterococci pose a significant threat in healthcare settings due to their resistance.
  • The plasticity of their genomes facilitates rapid adaptation and resistance development.
  • Effective treatment strategies are challenged by multi-drug resistance in Enterococcus infections.