Fusobacterium necrophorum sepsis after tonsillitis/pharyngitis
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Published on: November 16, 2015
Micheal Sheehan1, Darren McLoughlin1, Ronan O'Sullivan1
1Emergency Department, Cork University Hospital Group, Cork, Ireland.
Abstract:
Fusobacterium necrophorum is a rare infection most notable for causing Lemierre's syndrome. This consists of a primary oropharyngeal infection and septic thrombophlebitis, and one or more metastatic focus. Prior to the widespread use of antibiotics, Lemierre's syndrome commonly followed a rapidly progressing course, with a high mortality. We describe a case of a previously well 18-month-old boy who presented to the emergency department with a 3-week history of progressive, right-sided, painful neck swelling and systemic sepsis. He was initially treated conservatively with intravenous antibiotics, but ultimately required surgical drainage. Lemierre's syndrome is a rare condition with increasing incidence which can have significant adverse outcomes including death. Early recognition and treatment are essential, but identifying Lemierre's disease is challenging.
Insights
Fusobacterium necrophorum causes Lemierre's syndrome, a rare but serious infection. Early recognition and treatment are crucial for better outcomes in this challenging condition.
Area of Science:
- Microbiology
- Infectious Diseases
- Pediatrics
Background:
- Lemierre's syndrome, characterized by oropharyngeal infection and septic thrombophlebitis, is a rare but potentially fatal condition.
- Historically, Lemierre's syndrome had high mortality rates prior to antibiotic use.
Observation:
- A previously healthy 18-month-old boy presented with a three-week history of progressive right neck swelling and sepsis.
- The patient initially received intravenous antibiotics but required surgical intervention.
Findings:
- This case highlights the challenges in diagnosing Lemierre's syndrome, a condition caused by Fusobacterium necrophorum.
- Despite advancements, Lemierre's syndrome presents with increasing incidence and significant risks.
Implications:
- Early identification and prompt management are vital for improving patient outcomes and reducing mortality associated with Lemierre's syndrome.
- This case underscores the importance of considering rare infections like Lemierre's syndrome in pediatric patients with persistent neck masses and sepsis.
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