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Angiotensin inhibition in the developing kidney; tubulointerstitial effect

Kee Hwan Yoo1, Hyung Eun Yim2, Eun Soo Bae1

  • 1Department of Pediatrics, College of Medicine, Korea University, Seoul, 02841, Korea.

Pediatric Research
|February 1, 2019
PubMed
Summary

Neonatal enalapril treatment disrupts kidney lymphangiogenesis and promotes fibrosis in developing rat kidneys. This study reveals how blocking the renin-angiotensin system impacts renal development and interstitial collagen deposition.

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