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Related Concept Videos

Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

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Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
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Decreasing Function01:27

Decreasing Function

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A decreasing function describes a relationship where the output consistently declines as the input increases. This means that for any two input values, if one is greater than the other, the corresponding output is smaller. Mathematically, a function f is decreasing on an interval I if for every x1 < x2​ in I, f (x1) > f (x2). This type of behavior is visually identified on a graph that slopes downward from left to right.The nature of a function can be analyzed by calculating...
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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Decreased pulse rate01:14

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Bradycardia is a medical condition in which the heart rate is slower than normal. It occurs when the heart's natural pacemaker, the sinus node, generates slower electrical impulses than the standard rhythm. In adults, bradycardia is diagnosed when the pulse rate falls below 60 beats per minute, indicating a deviation from the normal heart rate range.
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Critical Region, Critical Values and Significance Level01:16

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The critical region, critical value, and significance level are interdependent concepts crucial in hypothesis testing.
In hypothesis testing, a sample statistic is converted to a test statistic using z, t, or chi-square distribution. A critical region is an area under the curve in  probability distributions demarcated by the critical value. When the test statistic falls in this region, it suggests that the null hypothesis must be rejected. As this region contains all those values of the...
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Related Experiment Video

Updated: Jan 30, 2026

Manual Muscle Testing: A Method of Measuring Extremity Muscle Strength Applied to Critically Ill Patients
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Tailored multicomponent program for discomfort reduction in critically ill patients may decrease post-traumatic

Pierre Kalfon1,2, Marine Alessandrini3, Mohamed Boucekine3

  • 1Réanimation Polyvalente, Hôpital Louis Pasteur, Hôpitaux de Chartres, 28018, Le Coudray, France. pkalfon@ch-chartres.fr.

Intensive Care Medicine
|February 1, 2019
PubMed
Summary
This summary is machine-generated.

A multicomponent program to reduce intensive care unit (ICU) discomfort significantly lowered post-traumatic stress disorder (PTSD) symptoms in survivors one year later. This intervention improves long-term outcomes for ICU patients.

Keywords:
Critical careDiscomfortICUPatient-reported outcomePost-traumatic stress disorderTailored program

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Area of Science:

  • Critical Care Medicine
  • Psychiatry
  • Health Outcomes Research

Background:

  • Intensive care unit (ICU) stays can lead to significant patient discomfort.
  • Reducing this discomfort is hypothesized to improve long-term health outcomes for survivors.
  • Post-traumatic stress disorder (PTSD) is a potential long-term consequence of critical illness.

Purpose of the Study:

  • To assess the effectiveness of a tailored multicomponent program for discomfort reduction in decreasing PTSD symptoms at one year among general ICU survivors.
  • To evaluate the impact of a discomfort reduction intervention on the long-term psychological well-being of critically ill patients.

Main Methods:

  • Prospective observational comparative effectiveness cohort study across 30 ICUs, extending the IPREA3 trial.
  • Intervention involved tailored multicomponent strategies: discomfort assessment, healthcare team feedback, and site-specific interventions.
  • One-year PTSD symptom prevalence was measured using the Impact of Event Scale-Revised (IES-R) in exposed versus unexposed ICU survivors.

Main Results:

  • A total of 1537 ICU survivors were included; 344 were exposed and 475 unexposed patients had one-year follow-up data.
  • The prevalence of substantial PTSD symptoms at one year was 6.1% in the exposed group versus 12.0% in the unexposed group (p=0.004).
  • After adjusting for covariates, exposed patients showed significantly lower likelihood of substantial PTSD symptoms at one year (p=0.015).

Conclusions:

  • A tailored multicomponent program effectively reduces self-perceived discomfort in general adult ICU survivors.
  • This discomfort reduction program also significantly decreased the prevalence of substantial PTSD symptoms at one year post-ICU discharge.