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Rare Persistent Corneal Infection by Phoma sp. - A Case Report.
Aspasia Adamopoulou1, Dimitris Sakellaris1, Spyridon Koronis1
1Ophthalmica Eye Institute, Vas Olgas 196 and Ploutonos 27, 54655, Thessaloniki, Greece.
Ophthalmology and Therapy
|February 1, 2019
Summary
A severe Phoma fungal eye infection occurred in a soft contact lens wearer in Greece. This case highlights the challenges in managing these difficult-to-treat corneal infections.
Area of Science:
- Ophthalmology
- Medical Mycology
- Infectious Diseases
Background:
- Fungal keratitis is a serious eye infection that can lead to vision loss.
- Phoma species are increasingly recognized as causative agents of fungal keratitis, particularly in contact lens wearers.
- Corneal infections caused by Phoma species present unique diagnostic and therapeutic challenges.
Purpose of the Study:
- To report the first case of severe Phoma species corneal infection in Greece.
- To illustrate the clinical presentation and management difficulties associated with Phoma keratitis.
- To highlight the multidisciplinary approach required for successful treatment.
Main Methods:
- Case report of a middle-aged female soft contact lens user with severe Phoma corneal infection.
- Clinical examination, microbiological investigations, and diagnostic imaging.
- Surgical interventions including corneal grafting and vitrectomy.
- Pharmacological treatment with intravitreal antibiotics.
Main Results:
- Successful treatment of severe Phoma keratitis through a combination of surgical and medical interventions.
- Demonstration of the recalcitrant nature of Phoma corneal infections.
- Confirmation of Phoma species as a potential cause of serious ocular morbidity in Greece.
Conclusions:
- Phoma species represent a significant cause of fungal keratitis, even in immunocompetent individuals using soft contact lenses.
- Management of Phoma keratitis requires a comprehensive and aggressive therapeutic strategy.
- Early diagnosis and prompt, appropriate treatment are crucial to prevent vision loss in fungal corneal infections.
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