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Magnetic resonance spectroscopy in vivo
1Division of Radiological Sciences, UMDS, Guy's Hospital, London, UK.
Journal of Biomedical Engineering
|November 1, 1988
Summary
Nuclear magnetic resonance spectroscopy (MRS) allows non-invasive in-vivo study of human tissue biochemistry. This technique measures phosphorus and proton metabolites in selected body regions using advanced magnetic field gradient methods.
Area of Science:
- Medical Imaging
- Biochemistry
- Non-invasive diagnostics
Background:
- Nuclear magnetic resonance (NMR) is a key non-invasive technique in medicine and biology.
- Recent advancements enable magnetic resonance spectroscopy (MRS) within specific human body regions.
Purpose of the Study:
- To detail the techniques for selecting specific regions for in-vivo magnetic resonance spectroscopy.
- To highlight the application of MRS in studying tissue biochemistry.
Main Methods:
- MRS utilizes techniques including surface coil methods, depth selection, volume selection, and chemical shift mapping.
- Volume selection and chemical shift mapping employ magnetic field gradients from magnetic resonance imaging (MRI) systems.
- MRS can measure phosphorus and proton metabolites.
Main Results:
- Specific regions within the human body can be targeted for MRS analysis.
- The study outlines categories of methods for precise volume selection in MRS.
- MRS enables the measurement of key metabolites like phosphorus and protons.
Conclusions:
- MRS is a powerful tool for non-invasive in-vivo biochemical analysis.
- The described techniques enhance the precision of MRS in targeting specific tissues.
- MRS facilitates the study of tissue biochemistry by measuring metabolites.