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Updated: Jan 30, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
Bilateral thalamic stroke in patient with patent foramen ovale and hereditary thrombophilia
M Yu Brovko1, L A Akulkina1, V I Sholomova1
1E.M. Tareev Clinic of Internal Diseases, I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Abstract:
Patent foramen ovale and hereditary thrombophilia are both known risk factors for ischemic stroke. Artery of Percheron is a rare anatomical variant in which vast areas of the midbrain and thalamus have a single source of blood supply. This case report presents a 45-years old female patient with bilateral thalamic stroke due to Percheron artery occlusion, with a combination of hereditary thrombophilia and patent foramen ovale as the risk factors. Modern approaches to the diagnosis and secondary prevention of this pathology are also discussed herein.
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