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Updated: Jan 30, 2026

Development of Compendium for Esophageal Squamous Cell Carcinoma
Published on: April 12, 2024
Primary Pleural Squamous Cell Carcinoma in a Free-Ranging River Otter (Lontra canadensis)
Norbert van de Velde1, Douglas J Demetrick2, Pádraig J Duignan3
11 Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium.
Abstract:
An adult female North American river otter (Lontra canadensis) presented with multiple intrathoracic masses identified histologically as squamous cell carcinoma. Immunohistochemical staining patterns for high- molecular-weight keratin, p40, p63, calretinin, and TTF-1, along with the gross and histologic findings, indicated a primary pleural squamous cell carcinoma as the most likely diagnosis.
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