Related Experiment Video

Updated: Jan 30, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.5K

Reported Knowledge and Management of Potential Penicillin Allergy in Children

David Vyles1, Rakesh D Mistry2, Viday Heffner3

  • 1Pediatric Emergency Medicine (D Vyles, V Heffner, P Drayna, and DC Brousseau),.

Academic Pediatrics
|February 1, 2019
PubMed

Insights

Pediatric emergency medicine and primary care providers often misclassify penicillin allergy symptoms. Both groups frequently label low-risk reactions as high-risk, impacting appropriate antibiotic use in children.

Area of Science:

  • Pediatric Allergy and Immunology
  • Clinical Pediatrics
  • Antibiotic Stewardship

Background:

  • Pediatric emergency medicine (PEM) and primary care providers (PCPs) are key in diagnosing penicillin allergy in children.
  • Existing research has not fully detailed knowledge and management differences regarding penicillin allergy between PEM and PCPs.

Purpose of the Study:

  • To compare the knowledge and management practices of PEM and PCPs concerning reported penicillin allergy in children.
  • To identify discrepancies in classifying penicillin allergy risk and in taking allergy histories.

Main Methods:

  • A cross-sectional study involving a 20-question survey administered to PEM and PCPs.
  • Statistical analysis (t tests, Chi-square, Wilcoxon tests) was used to compare knowledge of high- and low-risk symptoms and allergy history-taking extent.

Main Results:

  • PEM and PCPs reported similar percentages of children with low-risk symptoms tolerating penicillin (74.1% and 69.0%, respectively).
  • Both groups incorrectly identified common symptoms like vomiting and delayed rash as high-risk for penicillin allergy.
  • PCPs conducted more detailed allergy histories than PEM providers, and both groups expressed interest in using allergy questionnaires.

Conclusions:

  • Pediatric providers often acknowledge that children with remote low-risk allergy symptoms can tolerate penicillin, but this is not consistently applied in practice.
  • A tendency exists for both PEM and PCPs to over-classify low-risk penicillin allergy symptoms as high-risk, leading to under-referral for allergy assessment.
  • Both provider groups are open to decision support tools to improve penicillin allergy classification and promote appropriate antibiotic prescribing.
Abstract

Keywords:
general pediatricspediatric emergency departmentpenicillin allergy

More Related Videos

An Experimental Analysis of Children's Ability to Provide a False Report about a Crime07:36

An Experimental Analysis of Children's Ability to Provide a False Report about a Crime

Published on: May 3, 2016

9.0K
A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports07:35

A Knowledge Graph Approach to Elucidate the Role of Organellar Pathways in Disease via Biomedical Reports

Published on: October 13, 2023

2.2K

Related Concept Videos

Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
Types of Reports I: Hands-off Report01:25

Types of Reports I: Hands-off Report

A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
Potential Energy00:52

Potential Energy

The energy stored by a structure and location of matter in space is called potential energy. For instance, raising a kettlebell changes its spatial location and increases its potential energy. Similarly, a stretched rubber band contains potential energy which, under certain conditions, can be converted into other forms of energy, such as kinetic energy.
Chemical bonds that form attractive forces between atoms also contain potential energy, called chemical energy. When a chemical reaction...
42.7K
Types of Reports II: Incident or Occurrence Report01:21

Types of Reports II: Incident or Occurrence Report

An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.3K
Standard Electrode Potentials03:02

Standard Electrode Potentials

On comparing the reactivity of silver and lead, it is observed that the two ionic species, Ag+ (aq) and Pb2+ (aq), show a difference in their redox reactivity towards copper: the silver ion undergoes spontaneous reduction, while the lead ion does not. This relative redox activity can be easily quantified in electrochemical cells by a property called cell potential. This property is commonly known as cell voltage in electrochemistry, and it is a measure of the energy which accompanies the charge...
50.1K
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
292