Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microtubule Associated Proteins (MAPs)01:42

Microtubule Associated Proteins (MAPs)

5.9K
Microtubule function and architecture are regulated by an array of specialized proteins called microtubule-associated proteins or MAPs. These proteins are widespread across different organisms and have conserved protein motifs, like the multi-TOG domain for tubulin binding found in the CLASP family of MAPs. Some MAPs are lineage-specific based on their conserved domains. Their functions depend upon the cytoskeletal architecture and cell type they are located within. In-plant cells, a specific...
5.9K
Plotting of Topographic Maps01:29

Plotting of Topographic Maps

517
Topographic maps represent the Earth's surface features using contour lines, which connect points of equal elevation to create a two-dimensional representation of three-dimensional terrain. Creating a topographic map requires a systematic approach.Begin by plotting a scaled grid and marking intersections corresponding to the survey's elevation data points. Assign elevation values at these intersections to build the base map. Next, determine contour levels using a consistent contour interval,...
517
Coordinates and Map Projections01:29

Coordinates and Map Projections

611
Coordinates and map projections are essential tools in accurately representing the Earth's surface for various applications, ranging from navigation to spatial analysis. The latitude and longitude coordinate system is a universally recognized framework for defining locations. Latitude specifies the distance of a point north or south of the equator, measured in degrees from 0° at the equator to 90° at the poles. Longitude indicates a location's position east or west of the prime meridian,...
611
Case Studies01:22

Case Studies

13.5K
There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
13.5K
Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

344
Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
344
Longitudinal Studies01:26

Longitudinal Studies

521
Longitudinal studies are also widely used in other medical and social science fields. For instance, in cardiovascular research, they can monitor patients' health over decades to identify risk factors for heart disease, such as high cholesterol or smoking, and evaluate the long-term effectiveness of preventive measures. Similarly, in mental health studies, researchers might follow individuals from adolescence into adulthood to understand the development and progression of conditions like...
521

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Intracardiac Echocardiography and Coronary Angiography During Ventricular Ablation From the Aortic Cusps and Commissures: Marked Inter-Center Variability Without an Observed Coronary Injury Signal.

Journal of cardiovascular electrophysiology·2026
Same author

Trigger- vs Substrate-Based Purkinje De-Networking for Ventricular Fibrillation: Insights From a Multicenter Study.

JACC. Clinical electrophysiology·2026
Same author

Incidence of Worsening Aortic Regurgitation After Mapping and Ablation in the Aortic Cusps.

JACC. Clinical electrophysiology·2026
Same author

Adjunctive Purkinje Denetworking During Ventricular Tachycardia Ablation in Patients With Prior Ventricular Fibrillation.

JACC. Clinical electrophysiology·2026
Same author

Bridging anatomy and function in ischemic VT: CT wall-thickness and coherent mapping insights.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2026
Same author

Percutaneous renal sympathetic denervation combined with empirical Purkinje de-networking for electrical storm in congenital long QT syndrome after cardiac sympathetic denervation: a case report with two consecutive patients.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2026
Same journal

Yield of Family Screening in Arrhythmogenic Right Ventricular Cardiomyopathy Without a Validated Genetic Cause.

Circulation. Arrhythmia and electrophysiology·2026
Same journal

Effect of Exercise Training on Myocardial and Residual Scar Electrophysiology in Post-MI Rats.

Circulation. Arrhythmia and electrophysiology·2026
Same journal

Tau20-RETROmapping System Identifies Driver-Like Activation Patterns in Real-Time During Persistent Atrial Fibrillation.

Circulation. Arrhythmia and electrophysiology·2026
Same journal

Decreasing Microtubule Detyrosination Improves Cardiac Mechanics and Sodium Channel Function in Arrhythmogenic Cardiomyopathy.

Circulation. Arrhythmia and electrophysiology·2026
Same journal

cAMP-Activated EPAC Signaling Is an Integral Component of Cardiac Pacemaker Cell Automaticity.

Circulation. Arrhythmia and electrophysiology·2026
Same journal

Feasibility of Two-Dimensional Speckle-Tracking Echocardiography for Assessing Ablation Complexity in Left Ventricular Outflow Tract Premature Ventricular Contractions.

Circulation. Arrhythmia and electrophysiology·2026
See all related articles

Related Experiment Video

Updated: Jan 30, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

11.0K

Low Fluoroscopy Permanent His Bundle Pacing Using Electroanatomic Mapping: A Feasibility Study.

Parikshit S Sharma1, Henry D Huang1, Richard G Trohman1

  • 1Rush University Medical Center, Chicago, IL (P.S.S., H.D.H., R.G.T.).

Circulation. Arrhythmia and Electrophysiology
|February 2, 2019
PubMed
Summary
This summary is machine-generated.

Low fluoroscopy permanent His Bundle pacing (PHBP) using electroanatomic mapping is feasible and safe. This technique significantly reduces radiation exposure and fluoroscopy time compared to conventional methods.

Keywords:
His BundleHis Bundle pacingcardiac resynchronization therapyelectrophysiologyfluoroscopyradiation exposuresafety

More Related Videos

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

15.4K
Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
10:46

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

13.8K

Related Experiment Videos

Last Updated: Jan 30, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

11.0K
Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction
06:57

Ablation of Ischemic Ventricular Tachycardia Using a Multipolar Catheter and 3-dimensional Mapping System for High-density Electro-anatomical Reconstruction

Published on: January 31, 2019

15.4K
Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
10:46

Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology

Published on: May 26, 2015

13.8K

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Conventional permanent His Bundle pacing (PHBP) presents challenges, including significant fluoroscopy exposure.
  • Assessing novel techniques to mitigate these challenges is crucial for patient safety and procedural efficiency.

Purpose of the Study:

  • To evaluate the feasibility and safety of low-fluoroscopy PHBP utilizing 3-dimensional electroanatomic mapping.
  • To compare outcomes of this novel approach with conventional fluoroscopy-guided PHBP.

Main Methods:

  • A prospective study comparing 10 patients undergoing electroanatomic mapping-guided low-fluoroscopy PHBP (group 1) with 20 patients receiving conventional fluoroscopy-guided PHBP (group 2).
  • Key endpoints included procedural feasibility, total radiation exposure (fluoroscopy time, dose area product), and lead-related complications.

Main Results:

  • PHBP success rates were 90% in group 1 and 100% in group 2.
  • Group 1 demonstrated significantly lower mean His lead fluoroscopy time (0.2 min vs. 8 min), total fluoroscopy time (0.8 min vs. 13 min), and dose area product (96 vs. 1531 μGy/m²).
  • Lower His Bundle capture thresholds were observed in group 1 (0.7 vs. 1.15 at 1 ms), with no complications or lead dislodgements in either group.

Conclusions:

  • Electroanatomic mapping-guided PHBP is a feasible and safe alternative.
  • This method substantially reduces fluoroscopy duration and radiation exposure during PHBP implantation.