Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

What is the Immune System?01:38

What is the Immune System?

127.7K
Overview
127.7K
Humoral Immune Responses01:36

Humoral Immune Responses

83.8K
Overview
83.8K
Buffer Effectiveness02:19

Buffer Effectiveness

55.1K
Buffer solutions do not have an unlimited capacity to keep the pH relatively constant . Instead, the ability of a buffer solution to resist changes in pH relies on the presence of appreciable amounts of its conjugate weak acid-base pair. When enough strong acid or base is added to substantially lower the concentration of either member of the buffer pair, the buffering action within the solution is compromised.
The buffer capacity is the amount of acid or base that can be added to a given volume...
55.1K
Framing Effects03:26

Framing Effects

7.9K
Information is everywhere and its presentation—such as how and when items are presented—can impact our perceptions and decisions surrounding the info. This broad concept umbrellas framing effects—influences that occur due to the way information is framed in its appearance, whether it’s purely the order or the specific wording of a message. Let’s take a look at numerous ways in which two versions of something can objectively say the same thing, yet we respond in...
7.9K
Biological Effects of Radiation02:59

Biological Effects of Radiation

17.9K
All radioactive nuclides emit high-energy particles or electromagnetic waves. When this radiation encounters living cells, it can cause heating, break chemical bonds, or ionize molecules. The most serious biological damage results when these radioactive emissions fragment or ionize molecules. For example, α and β particles emitted from nuclear decay reactions possess much higher energies than ordinary chemical bond energies. When these particles strike and penetrate matter, they...
17.9K
Active versus Passive Immunity01:31

Active versus Passive Immunity

10.7K
Immunity, along with the ability to limit pathogen growth to prevent significant body tissue damage, can be gained either by (1) actively developing an immune response within the individual after exposure to a pathogen or after getting vaccinated or (2) passively transferring immune components from an immune individual to one who is nonimmune. Both these forms of immunity can be found naturally and in medical practices.
Active Immunity
Active immunity refers to the resistance one develops...
10.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Author Correction: AI based predictive acceptability model for effective vaccine delivery in healthcare systems.

Scientific reports·2025
Same author

Comprehensive Characterization of the Odor-Active Compounds in Different Processed Varieties of Yunnan White Tea (<i>Camellia sinensis</i>) by GC×GC-O-MS and Chemometrics.

Foods (Basel, Switzerland)·2025
Same author

Xylooligosaccharides: A comprehensive review of production, purification, characterization, and quantification.

Food research international (Ottawa, Ont.)·2025
Same author

Correction: Unveiling the obstacles encountered by women doctors in the Pakistani healthcare system: A qualitative investigation.

PloS one·2025
Same author

TargetCLP: clathrin proteins prediction combining transformed and evolutionary scale modeling-based multi-view features via weighted feature integration approach.

Briefings in bioinformatics·2025
Same author

Systematic Review of Vaccine Strategies Against Tritrichomonas foetus Infection in Cattle: Insights, Challenges, and Prospects.

Parasite immunology·2025

Related Experiment Video

Updated: Jan 30, 2026

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
09:16

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

15.8K

Methamphetamine and its immune-modulating effects.

Marco Papageorgiou1, Ali Raza1, Sarah Fraser1

  • 1Institute for Health and Sport, Victoria University, Melbourne, VIC, Australia.

Maturitas
|February 2, 2019
PubMed
Summary
This summary is machine-generated.

Methamphetamine (METH) use impacts the immune system, leading to neurological issues and increased disease risk. Understanding these immune pathways is crucial for addressing METH

Keywords:
Drug addictionIceInflammationMETHMethamphetamineSignaling pathways

More Related Videos

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

15.1K
siRNA Electroporation to Modulate Autophagy in Herpes Simplex Virus Type 1-Infected Monocyte-Derived Dendritic Cells
09:10

siRNA Electroporation to Modulate Autophagy in Herpes Simplex Virus Type 1-Infected Monocyte-Derived Dendritic Cells

Published on: October 28, 2019

7.7K

Related Experiment Videos

Last Updated: Jan 30, 2026

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
09:16

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

Published on: January 22, 2016

15.8K
Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles
09:15

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles

Published on: November 10, 2017

15.1K
siRNA Electroporation to Modulate Autophagy in Herpes Simplex Virus Type 1-Infected Monocyte-Derived Dendritic Cells
09:10

siRNA Electroporation to Modulate Autophagy in Herpes Simplex Virus Type 1-Infected Monocyte-Derived Dendritic Cells

Published on: October 28, 2019

7.7K

Area of Science:

  • Neuroimmunology
  • Psychopharmacology
  • Public Health

Background:

  • Recreational methamphetamine (METH) use is a significant global health issue affecting millions worldwide.
  • METH is a highly addictive psychotropic substance impacting the central nervous system and potentially inducing psychosis.
  • Chronic METH use can alter immune cell function, leading to long-term neuropsychiatric disorders and increased susceptibility to infections like HIV.

Purpose of the Study:

  • To explore the multifaceted impact of METH on host immunity via neurological and peripheral modifications.
  • To investigate how METH influences immune-related signaling pathways and inflammatory responses.
  • To understand METH's role in premature aging and exacerbation of non-communicable age-related diseases.

Main Methods:

  • Review and synthesis of current data on METH's effects on immune cells and signaling pathways.
  • Analysis of the relationship between METH-induced cytokine imbalance, blood-brain barrier integrity, and neurotoxicity.
  • Integration of knowledge on inflammatory responses with neurological and peripheral immune changes.

Main Results:

  • METH modulates immune cells, causing lasting effects that may manifest as neuropsychiatric disorders.
  • Changes in cytokine balance compromise the blood-brain barrier, leading to altered brain plasticity and neurotoxicity.
  • METH use is linked to increased susceptibility to communicable diseases and exacerbation of age-related diseases.

Conclusions:

  • Immune-related signaling pathways are critical for understanding METH's impact on host immunity.
  • METH can accelerate aging processes and worsen conditions like cardiovascular disease, stroke, depression, and dementia.
  • Further research into these pathways is essential for developing effective interventions against METH's widespread health consequences.