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Danshen: a phytochemical and pharmacological overview.
Xiao-Dan MEIm1, Yan-Feng Cao1, Yan-Yun Che2
1School of Chinese Pharmacy, Beijing University of Chinese Medicine, Beijing 102488, China.
Chinese Journal of Natural Medicines
|February 2, 2019
Summary
Danshen (Salvia miltiorrhiza) is a traditional Chinese medicine with over 200 compounds identified. This review covers its uses, pharmacology, and potential for improved utilization.
Area of Science:
- Herbal Medicine
- Pharmacology
- Traditional Asian Medicine
Background:
- Danshen, derived from Salvia miltiorrhiza, is a widely used traditional and folk medicine in Asia.
- Its historical applications and preparations are well-documented.
Purpose of the Study:
- To review recent research on Danshen.
- To summarize its traditional uses, chemical constituents, pharmacological activities, and side effects.
- To provide insights for enhancing Danshen's utilization.
Main Methods:
- Literature review of recent scientific research on Danshen.
- Compilation of reported chemical compounds and their properties.
- Summary of documented pharmacological activities and adverse effects.
Main Results:
- Over 201 compounds have been identified in Danshen.
- These compounds include lipophilic diterpenoids and water-soluble phenolic acids.
- Pharmacological activities include anti-inflammatory, antioxidant, anti-tumor, anti-atherogenesis, and anti-diabetic effects.
Conclusions:
- Danshen possesses diverse pharmacological properties attributed to its rich chemical composition.
- Further research can optimize the use of Danshen in traditional and modern medicine.
- Understanding its constituents and activities is key to enhancing its therapeutic value.
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