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Published on: February 24, 2023
Mycoplasma Pneumoniae Pericarditis
Aishwarya Vijay1, John C Stendahl2, Lynda E Rosenfeld2
1Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Abstract:
Mycoplasma pneumoniae is an atypical bacterium that is frequently implicated in respiratory infections, but uncommonly identified as a cause of pericarditis. We report 2 cases of pericarditis attributed to M. pneumoniae that were characterized by prolonged respiratory prodromes, pericardial, and pleural effusions, elevated inflammatory markers, and relapsing clinical courses. In conclusion, our experience suggests that M. pneumoniae should be considered as a potential cause in cases of pericarditis associated with upper respiratory symptoms, pneumonia, pleural effusions, arthralgia, and/or a recurrent/refractory clinical course. The availability of effective antibiotic treatment makes this an important diagnosis to make.
Insights
Mycoplasma pneumoniae, a cause of respiratory infections, can also lead to pericarditis. Consider this atypical bacterium in patients with persistent respiratory symptoms and relapsing pericarditis for effective antibiotic treatment.
Area of Science:
- Infectious Diseases
- Cardiology
- Pulmonology
Background:
- Mycoplasma pneumoniae commonly causes respiratory infections.
- Pericarditis is an uncommon manifestation of M. pneumoniae infection.
- Prompt diagnosis is crucial due to effective antibiotic therapies.
Purpose of the Study:
- To highlight Mycoplasma pneumoniae as a potential cause of pericarditis.
- To describe clinical characteristics of M. pneumoniae-associated pericarditis.
- To emphasize the importance of considering M. pneumoniae in refractory pericarditis cases.
Main Methods:
- Case report of two patients with pericarditis attributed to M. pneumoniae.
- Clinical data collection including symptoms, diagnostic findings, and treatment outcomes.
- Review of literature on M. pneumoniae and pericarditis.
Main Results:
- Two cases of pericarditis linked to M. pneumoniae infection presented with prolonged respiratory symptoms.
- Patients exhibited pericardial and pleural effusions, elevated inflammatory markers, and relapsing clinical courses.
- M. pneumoniae was identified as the causative agent in both cases.
Conclusions:
- Mycoplasma pneumoniae should be considered in pericarditis cases with preceding respiratory symptoms, effusions, or recurrent disease.
- Recognition of M. pneumoniae as a cause of pericarditis facilitates targeted antibiotic treatment.
- This diagnosis is critical for managing patients with atypical pericarditis and associated respiratory illness.
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