Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structure and Function of Platelets01:18

Structure and Function of Platelets

3.5K
The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
3.5K
Responses to Heat and Cold Stress02:45

Responses to Heat and Cold Stress

14.8K
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
14.8K
Energy Stored in a Capacitor01:12

Energy Stored in a Capacitor

4.6K
When an archer pulls the string in a bow, he saves the work done in the form of elastic potential energy. When he releases the string, the potential energy is released as kinetic energy of the arrow. A capacitor works on the same principle in which the work done is saved as electric potential energy. The potential energy (UC) could be calculated by measuring the work done (W) to charge the capacitor.
4.6K
Transfer Function in Control Systems01:21

Transfer Function in Control Systems

1.6K
The transfer function is a fundamental concept in the analysis and design of linear time-invariant (LTI) systems. It offers a concise way to understand how a system responds to different inputs in the frequency domain. It serves as a bridge between the time-domain differential equations that describe system dynamics and the frequency-domain representation that facilitates easier manipulation and analysis.
To derive the transfer function, consider a general nth-order linear time-invariant...
1.6K
Energy Stored in Capacitors01:10

Energy Stored in Capacitors

1.1K
A parallel plate capacitor, when connected to a battery, develops a potential difference across its plates. This potential difference is key to the operation of the capacitor, as it determines how much electrical energy the capacitor can store.
By integrating the equation that relates voltage and current in a capacitor, one can derive an equation for the voltage across the capacitor at any given time. This equation is crucial in understanding and predicting the behavior of capacitors in...
1.1K
Energy Stored in Inductors01:16

Energy Stored in Inductors

945
An inductor is ingeniously crafted to accumulate energy within its magnetic field. This field is a direct result of the current that meanders through its coiled structure. When this current maintains a steady state, there is no detectable voltage across the inductor, prompting it to mimic the behavior of a short circuit when faced with direct current.
In terms of gauging the energy stored within an inductor, it is equivalent to the integral of the power delivered at every individual moment, all...
945

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Novel anticoagulant-preservative solution maintained the hemostatic function of cold stored whole blood for 56 days.

Transfusion·2025
Same author

Clinicopathological investigation of nutritional osteodystrophia fibrosa in a flock of young stall-fed goats.

Iranian journal of veterinary research·2024
Same author

Evaluating the effects of hypoxic storage on platelet function and health using a novel storage system.

Transfusion·2024
Same author

Targeting PP2A and proteasome activity ameliorates features of allergic airway disease in mice.

Allergy·2017
Same author

Refrigerated platelets stored in whole blood up to 5 days adhere to thrombi formed during hemorrhagic hypotension in rats.

Journal of thrombosis and haemostasis : JTH·2016
Same author

A pathogenic role for tumor necrosis factor-related apoptosis-inducing ligand in chronic obstructive pulmonary disease.

Mucosal immunology·2015
Same journal

Therapeutic plasma exchange in Alzheimer's disease: From clinical trial to real-world evidence.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

Successful treatment of pure red cell aplasia with Orelabrutinib following major ABO-incompatible hematopoietic stem cell transplantation for acute myeloid leukemia: A case report.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

Technological advances in selective plasma adsorption: The MTx.100 column and the emergence of subtractive precision medicine.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

What's happening? Editorial comment: Insights on artificial intelligence, cell therapy and stem cell transplantation safety.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

Red blood cell transfusion in elderly patients: Hemoglobin thresholds and clinical outcomes.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

A personalized view on how artificial intelligence will change the future of multidirectional cell therapy: From design and engineering foundation to some healthcare applications.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
See all related articles

Related Experiment Video

Updated: Jan 30, 2026

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.7K

Cold-stored platelets: A product with function optimized for hemorrhage control.

K M Reddoch-Cardenas1, J A Bynum1, M A Meledeo1

  • 1Coagulation and Blood Research Program, U.S. Army Institute of Surgical Research, Fort Sam Houston, TX, 78234, United States.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|February 2, 2019
PubMed
Summary
This summary is machine-generated.

Early transfusion of blood products, especially platelets, is crucial for trauma patients. Cold-stored platelets offer a promising alternative to room temperature storage, potentially improving hemostasis and reducing bacterial risks.

Keywords:
Cold stored plateletsCold stored whole bloodPlatelet transfusionTherapeutic transfusion

More Related Videos

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
12:40

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Published on: December 7, 2012

29.5K
A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation
06:50

A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation

Published on: June 10, 2020

2.3K

Related Experiment Videos

Last Updated: Jan 30, 2026

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.7K
Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System
12:40

Preparation and Pathogen Inactivation of Double Dose Buffy Coat Platelet Products using the INTERCEPT Blood System

Published on: December 7, 2012

29.5K
A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation
06:50

A Preclinical Controlled Cortical Impact Model for Traumatic Hemorrhage Contusion and Neuroinflammation

Published on: June 10, 2020

2.3K

Area of Science:

  • Trauma care and transfusion medicine

Background:

  • Early hemostasis is critical for severe trauma outcomes.
  • Platelet transfusions rapidly control bleeding and correct trauma-induced dysfunction.
  • Current U.S. platelet storage at room temperature has a 5-7 day limit and risks bacterial growth and functional decline.

Purpose of the Study:

  • To review the current status of cold-stored platelets and cold-stored whole blood for actively bleeding patients.
  • To discuss the potential applications of cold-stored platelets in regenerative medicine.

Main Methods:

  • Literature review of cold-stored platelets and whole blood in trauma and regenerative medicine.

Main Results:

  • Cold storage of platelets and whole blood is being re-evaluated for therapeutic transfusion in trauma.
  • Cold storage may mitigate risks associated with room temperature storage, such as bacterial contamination and reduced function.

Conclusions:

  • Cold-stored platelets and whole blood show potential for treating actively bleeding trauma patients.
  • Further research into cold storage applications, including regenerative medicine, is warranted.