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Remote photoacoustic sensing using speckle-analysis.

Benjamin Lengenfelder1,2, Fanuel Mehari3,4, Martin Hohmann3,4

  • 1Institute of Photonic Technologies (LPT), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Konrad-Zuse-Straße 3/5, 91052, Erlangen, Germany. Benjamin.Lengenfelder@lpt.uni-erlangen.de.

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Summary
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Researchers developed a novel remote sensing technique for photoacoustic imaging, enhancing laser surgery feedback. This non-contact method improves tissue visualization and could expand laser applications in surgery.

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Area of Science:

  • Biomedical Optics
  • Surgical Technology
  • Acoustic Imaging

Background:

  • Laser surgery offers advantages over traditional methods but lacks real-time, non-contact feedback for tissue identification.
  • Current photoacoustic imaging techniques often require physical contact, limiting their application in laser surgery.
  • A high-contrast, deep-penetrating imaging system is needed for effective laser surgery guidance.

Purpose of the Study:

  • To introduce a novel non-interferometric, remote detection technique for photoacoustic imaging.
  • To demonstrate the feasibility of speckle analysis for non-contact photoacoustic detection.
  • To explore the potential of this technique as a feedback system for laser surgery.

Main Methods:

  • Development of a non-interferometric photoacoustic detection technique utilizing speckle analysis.
  • Implementation of remote sensing for photoacoustic signal acquisition.
  • Validation through phantom and ex-vivo experiments in both transmission and reflection modes.

Main Results:

  • The study successfully demonstrated a remote speckle sensing technique for photoacoustic detection.
  • Proof-of-concept was established using phantom and ex-vivo samples.
  • The technique shows potential for non-contact, high-contrast imaging.

Conclusions:

  • The developed remote speckle sensing technique is a viable method for non-contact photoacoustic detection.
  • This technology holds promise for integration as a real-time feedback system in laser surgery.
  • It could significantly enhance the capabilities and applications of lasers in surgical procedures.