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Plasma transfusions in horses with typhlocolitis/colitis
Luis G Arroyo1, William Sears1, Diego E Gomez1
1Departments of Clinical Studies (Arroyo) and Population Medicine (Sears), Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1; Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA (Gomez).
The Canadian Veterinary Journal = La Revue Veterinaire Canadienne
|February 2, 2019
Summary
Plasma transfusions for horses with typhlocolitis/colitis were evaluated. Transfused horses had higher mortality rates, questioning the clinical benefit of plasma therapy in these cases.
Area of Science:
- Veterinary Medicine
- Equine Health
- Critical Care
Background:
- Typhlocolitis/colitis is a serious condition in horses.
- Hypoproteinemia is a common complication requiring treatment.
- Plasma transfusions are a potential therapeutic option.
Purpose of the Study:
- To evaluate the outcome of plasma transfusions in horses diagnosed with typhlocolitis/colitis.
- To determine the association between plasma therapy and survival rates in affected horses.
Main Methods:
- Retrospective case series analysis.
- Evaluation of treatment outcomes at a veterinary teaching hospital.
- Comparison of mortality rates between transfused and non-transfused horses.
Main Results:
- Horses with typhlocolitis/colitis receiving plasma transfusions exhibited increased odds of mortality.
- Plasma therapy was associated with poorer outcomes in this cohort.
- Survival analysis indicated a negative impact of transfusions.
Conclusions:
- The clinical utility of plasma transfusions for hospitalized hypoproteinemic horses with typhlocolitis/colitis is questionable.
- Further research is needed to clarify the role of plasma therapy in equine critical care.
- Alternative or adjunctive treatments may be more beneficial.
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