Related Experiment Video
Updated: Jan 30, 2026

12:03
Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
28.7K
Functional outcomes of traumatic lower extremity reconstruction
Alexis D Rounds1, Karen E Burtt1, Hyuma A Leland2
1Keck School of Medicine of University of Southern California, 1975 Zonal Avenue, Los Angeles, CA 90033, United States.
Journal of Clinical Orthopaedics and Trauma
|February 2, 2019
Summary
Soft tissue reconstruction for open tibia fractures significantly improves patient function, with 70% returning to pre-injury levels. Local tissue flaps promote earlier ambulation after lower extremity trauma.
Area of Science:
- Orthopedic surgery
- Trauma reconstruction
- Functional outcomes research
Background:
- Lower extremity trauma is a common injury, with over 300,000 cases annually.
- Soft tissue transfer is a standard procedure for open fracture coverage.
- Functional outcomes after soft tissue transfer for open fractures require further investigation.
Purpose of the Study:
- To evaluate functional outcomes after soft tissue reconstruction in patients with open tibial fractures.
- To identify factors influencing functional recovery and ambulation.
Main Methods:
- Retrospective review of a prospectively maintained database.
- Inclusion of open tibia fractures requiring soft tissue reconstruction.
- Data collected from October 2013 to March 2015 at a Level 1 trauma center.
Main Results:
- The study analyzed 30 patients with various Gustilo-Anderson fracture types (I-IIIc).
- Both local flaps and free tissue transfers were utilized for definitive closure.
- Seventy percent of patients achieved full ambulation, and local flap use predicted earlier discharge ambulation.
Conclusions:
- Soft tissue reconstruction leads to favorable functional recovery in most patients with open tibial fractures.
- Local tissue flaps are associated with improved and earlier ambulation outcomes.
- Further research can optimize reconstructive strategies for better functional results.
Related Concept Videos
Predicting Reaction Outcomes
10.8K
Kinetics describes the rate and path by which a reaction occurs. In contrast, thermodynamics deals with state functions and describes the properties, behavior, and components of a system. It is not concerned with the path taken by the process and cannot address the rate at which a reaction occurs. Although it does provide information about what can happen during a reaction process, it does not describe the detailed steps of what appears on an atomic or a molecular level. On the other hand,...
10.8K
Outcomes of Glycolysis
107.1K
Nearly all the energy used by cells comes from the bonds that make up complex organic compounds. These organic compounds are broken down into simpler molecules, such as glucose. As a result, cells extract energy from glucose over many chemical reactions—a process called cellular respiration.
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
Cellular respiration can occur aerobically (with oxygen) or anaerobically (without oxygen). In the presence of oxygen, cellular respiration starts with glycolysis and continues with pyruvate...
107.1K
Absolute and Local Extreme Values
68
The highest and lowest values of a function, relative to a reference axis, are known as extreme values. These include absolute maximum and absolute minimum values, which represent the highest and lowest points the function reaches across its entire domain. Within a restricted portion of the function, the highest and lowest values are referred to as local maximum and local minimum values, respectively.Periodic functions, such as sine and cosine, show extreme values at infinitely many points due...
68
Traumatic Memory
579
Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
579
Guidelines for Writing Outcome
3.8K
When developing expected outcomes for a patient care plan, the nurse should adhere to the following recommendations:
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...
3.8K
Reconstruction of Signal using Interpolation
726
Signal processing techniques are essential for accurately converting continuous signals to digital formats and vice versa. When a continuous signal is sampled with a period T, the resulting sampled signal exhibits replicas of the original spectrum in the frequency domain, spaced at intervals equal to the sampling frequency. To handle this sampled signal, a zero-order hold method can be applied, which creates a piecewise constant signal by retaining each sample's value until the next...
726

