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Updated: Jan 30, 2026

Understanding Cerebellar Pattern Formation
Published on: November 1, 2007
Association of Klippel-Feil syndrome, Dandy-Walker malformation, spina bifida: A case report
Alessio Pirino1, Maria Alessandra Sotgiu1, Erich Cosmi2
1Department of Biomedical Sciences, University of Sassari, Sassari, Italy.
Abstract:
Klippel-Feil syndrome is a congenital malformation characterized by the fusion of at least 2 cervical vertebrae. It may occur in association with other clinical syndromes and disorders. We describe a case of prenatal diagnosis of a Klippel-Feil syndrome with Dandy-Walker malformation, and spina bifida, proved by ultrasound examination. A postmortem x-ray and autopsy were performed in a female fetus of 16 + 6 weeks of gestation: several malformations have been discovered. To the best of our knowledge, no similar cases have been reported in the medical literature. This case report underscores the importance of a careful ultrasound screening during pregnancy for an adequate diagnostic and therapeutic management.
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