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Pharmacological Adjuncts to Vitrectomy Surgery.

Maria C Savastano1, Alfonso Savastano2, Stanislao Rizzo3

  • 1Centro Italiano Macula, Rome, Italy.

Current Pharmaceutical Design
|February 2, 2019
PubMed
Summary
This summary is machine-generated.

Pharmacological adjuncts enhance vitrectomy surgery outcomes. This review classifies these agents by their timing: pre-operative, intra-operative, and post-operative use, aiding vitreoretinal surgical practice.

Keywords:
Anti-VEGFadjuvant therapy (post-operative)corticosteroidsintra-operative adjuvantintravitreal antibioticsintravitreal antifungalintravitreal dyeintravitreal tamponadeneo-adjuvant therapy (pre-operative)vitrectomy surgery.

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Area of Science:

  • Ophthalmology
  • Surgical Pharmacology

Background:

  • Pharmacological adjuncts are crucial for optimizing vitrectomy surgery.
  • These agents expand therapeutic options across all surgical phases.

Purpose of the Study:

  • To classify pharmacological adjuncts used in vitrectomy surgery based on their application timing.
  • To provide a framework for understanding their roles in pre-operative, intra-operative, and post-operative settings.

Main Methods:

  • Literature review and classification of pharmacological adjuncts.
  • Categorization based on therapeutic use: neo-adjuvant (pre-operative), intra-operative, and adjuvant (post-operative).

Main Results:

  • Pharmacological adjuncts are categorized into three main groups based on surgical timing.
  • This classification aids in understanding the strategic application of these agents.

Conclusions:

  • A timing-based classification (pre-operative, intra-operative, post-operative) effectively organizes pharmacological adjuncts for vitrectomy.
  • Emerging molecules are expected to further enhance vitreoretinal surgical aid.