Related Experiment Video
Updated: Jan 30, 2026

TBase - an Integrated Electronic Health Record and Research Database for Kidney Transplant Recipients
Published on: April 13, 2021
Beyond One-Off Integrations: A Commercial, Substitutable, Reusable, Standards-Based, Electronic Health
Kenneth D Mandl1,2, Daniel Gottlieb1,2, Alyssa Ellis1
1Computational Health Informatics Program, Boston Children's Hospital, Boston, MA, United States.
The Substitutable Medical Apps and Reusable Technology (SMART) Health IT project uses open APIs to enable scalable medical apps. This approach accelerates innovation and commercial success for health technology startups.
Area of Science:
- Health Informatics
- Health Information Technology
- Software Engineering
Background:
- The Substitutable Medical Apps and Reusable Technology (SMART) Health IT project initiated in 2010.
- SMART promotes the development of scalable and substitutable medical applications.
- An open application programming interface (API) specification is central to the SMART initiative.
Purpose of the Study:
- To demonstrate how a universal open API can accelerate commercial success for health IT startups.
- To illustrate the benefits of substitutable medical apps and open app stores.
- To showcase a scalable approach for health IT innovation diffusion.
Main Methods:
- The SMART project defined an open API specification for connecting apps to electronic health records (EHRs) and data warehouses.
- The Meducation app was developed as a SMART-enabled application by Polyglot.
- The app was distributed through the SMART App Gallery, an open app store.
Main Results:
- The SMART-enabled Meducation app achieved widespread implementation across numerous US hospitals and clinics.
- The use of a universal, open API allowed one project manager to handle up to 20 simultaneous app implementations.
- The SMART App Gallery facilitated app discovery and fostered market competition through substitutability.
Conclusions:
- A universal open API for patient and clinician-facing health IT systems significantly supports and accelerates commercial success for startups.
- Providing end-users with a diverse and expanding selection of apps via a universal open API promotes rapid innovation diffusion across health systems.
- The SMART approach offers a promising and generalizable model for advancing health technology.
Related Concept Videos
Purpose of Health Records I
Here's a breakdown of how health records serve these purposes:
Purpose of Health Records II
Substitution Rule Applied to Indefinite Integrals
Substitution Rule Applied to Definite Integrals
Standard Electrode Potentials
Data Reporting and Recording

