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Toward a Core Outcome Measurement Set for Polymyalgia Rheumatica: Report from the OMERACT 2018 Special Interest Group
Claire E Owen1,2, Max Yates3,4, Helen Twohig3,4
1From the Department of Rheumatology, Austin Health; Department of Medicine, University of Melbourne, Melbourne; Rheumatology Unit, Royal Adelaide Hospital; Discipline of Medicine, The University of Adelaide, Adelaide, Australia; Department of Rheumatology, Addenbrooke's Hospital, Cambridge; Norwich Medical School, University of East Anglia, Norwich; Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Keele; PMR-GCA Scotland, Dundee, Angus; PMR-GCA North East, Kibblesworth, Tyne and Wear; Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds; UK National Institute for Health Research (NIHR)-Leeds Biomedical Research Centre, Leeds Teaching Hospitals National Health Service (NHS) Trust, Leeds, UK; Ottawa Hospital Research Institute; School of Epidemiology, Public Health and Preventative Medicine, University of Ottawa, Ottawa, Ontario, Canada; SDG LLC, Cambridge, Massachusetts, USA. claire.owen@austin.org.au.
Objective:
To report the progress of the Outcome Measures in Rheumatology (OMERACT) Polymyalgia Rheumatica (PMR) Working Group in selecting candidate instruments for a core outcome measurement set.
Methods:
A systematic literature review identified outcomes measured and instruments used in PMR studies, and a respondent survey and raw data analysis assessed their domain match and feasibility.
Results:
Candidate instruments were identified for pain [visual analog scale/numerical rating scale (VAS/NRS)], stiffness (VAS/NRS and duration), and physical function (Health Assessment Questionnaire-Disability Index/modified Health Assessment Questionnaire). Domain match and feasibility assessments were favorable; however, validation in PMR was lacking.
Conclusion:
Further assessment of candidate instruments is required prior to recommending a PMR core outcome measurement set.
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