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Updated: Aug 14, 2026

Evaluation of Injury-induced Senescence and In Vivo Reprogramming in the Skeletal Muscle
Published on: October 26, 2017
[The skin in the elderly]
1Ludwig-Boltzmann-Institut für dermatovenerologische Serodiagnostik, Wien, Osterreich.
Abstract:
Skin changes in advanced age consist mainly of an atrophy of the epidermis and of the appendices as well as of degeneration within the corium which cause asteatosis, purpura, de and hyperpigmentation and elastosis. The regulation of the body-temperature is altered. The influence of light leads up to actinic keratoses and to skin cancer. Diseases of the sebaceous glands and seborrheic dermatoses are rarely seen in the aged. Tumors of the skin occur in about 4% of persons in their forties but in 20% at 70 years of age. Systemic treatment has to take into consideration an increased inclination to complications and frequently also a reduced effect due to decreased blood circulation in the skin. Ointment bases consisting of oil/water emulgations with addition of fat or water are usually well tolerated. The use of soap and detergents should be restricted. The application of ointments containing UV filter substances is recommended at sun exposure.
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