Related Experiment Video
Updated: Jan 29, 2026

Whole-mount Imaging of Mouse Embryo Sensory Axon Projections
Published on: December 9, 2014
Thalamostriatal projections and striosome-matrix compartments
Fumino Fujiyama1, Tomo Unzai1, Fuyuki Karube1
1Laboratory of Neural Circuitry, Graduate School of Brain Science, Doshisha University, Kyoto, 610-0394, Japan.
Abstract:
The neostriatum has a mosaic organization consisting of striosome and matrix compartments. It receives glutamatergic excitatory afferents from the cerebral cortex and thalamus. Recent behavioral studies in rats revealed a selectively active medial prefronto-striosomal circuit during cost-benefit decision-making. However, clarifying the input/output organization of striatal compartments has been difficult because of its complex structure. We recently demonstrated that the source of thalamostriatal projections are highly organized in striatal compartments. This finding indicated that the functional properties of striatal compartments are influenced by their cortical and thalamic afferents, presumably with different time latencies. In addition, these afferents likely support the unique dynamics of striosome and matrix compartments. In this manuscript, we review the anatomy of basal ganglia networks with regard to striosome/matrix structure. We place specific focus on thalamostriatal projections at the population and single neuron level.
Related Concept Videos
Fischer Projections
Newman Projections
The organic molecules rotate across the single bonds leading to numerous temporary three-dimensional structures of varying energy known as...
Compartment Models: Two-Compartment Model
Compartment Models: Single-Compartment Model
The Extracellular Matrix
Three-Compartment Open Model

